Gb Sciences Identifies Novel Cannabis-Inspired Mixtures as Anti-Inflammatory Therapies Based on Proprietary AI-Enabled Drug Discovery Platform

Gb Sciences Identifies Novel Cannabis-Inspired Mixtures as Anti-Inflammatory Therapies Based on Proprietary AI-Enabled Drug Discovery PlatformGb Sciences’ innovative approach harnesses the power of plant-based treatments as simplified mixtures that target dangerous hyperinflammatory responses to viral infections.

LAS VEGAS – December 22, 2022 – (Newswire.com)

Gb Sciences, Inc. (OTCQB:GBLX), a leading plant-inspired, biopharmaceutical research and development company, is developing cannabis-inspired anti-inflammatory therapeutics that address Cytokine Release Syndrome (CRS) caused by viral infections like COVID-19 and others. Over the two pandemic years, more than 540 million people across the world contracted COVID-19 and 6.3 million died from the hyperinflammatory side effects related to this viral infection, which inspired Gb Sciences to create anti-inflammatory drugs designed to treat future viral outbreaks that elicit these dangerous hyperinflammatory responses. 

The global anti-inflammatory therapeutics market size was estimated at USD 99.6 billion in 2021, according to Precedence Research, and is expected to hit USD 127.5 billion by 2030, with a registered CAGR of 4.5% from 2022 to 2030. Gb Sciences announced in May 2022 that FHI Clinical would consult and write the draft clinical trial protocol for a first-in-human trial of these proprietary cannabinoid-containing formulations. One key differentiator of Gb Sciences’ CRS therapeutic is the early-intervention and preventative opportunities for patients when they first discover they have been exposed to a virus that causes hyperinflammation. This therapeutic may also be useful for patients who are experiencing CRS as a side effect of certain new cancer therapeutics, such as Bispecific T-cell engaging (BiTE) single-chain antibody constructs and chimeric antigen receptor (CAR) T-cells.

“Our research shows promise for the potential use of cannabinoids within cannabinoid-containing mixtures as a treatment option for hyperinflammation. There is still a need for effective treatments to combat the hyperinflammatory effects of certain viruses. Our cannabis-inspired therapeutics were designed to reset the immune system after hyperinflammation has been triggered, providing relief by targeting our human immune response to a virus, without being tied to a specific variant or the virus itself,” said Andrea Small-Howard, President and Chief Science Officer of Gb Sciences.

Gb Sciences used PhAROS™, its proprietary AI-enabled drug discovery platform, to identify these therapeutic mixtures that were designed to reduce the levels of specific cytokines and pro-inflammatory processes triggered by viruses, while preserving the immune functions and cytokines necessary to fight viral infections. Gb Sciences recently published a white paper on their novel development program titled “Utilizing Proprietary AI/ML Technology, Novel Cannabis-Inspired Mixtures Are Developed as Innovative Anti-Inflammatory Therapeutics”; download it here

A proof-of-concept study completed by researchers at Michigan State University in 2021 found that Gb Sciences’ proprietary cannabis-inspired minimum essential mixtures (MEM) reduced cytokine release syndrome biomarkers. Gb Sciences’ MEM, containing either two or three cannabinoids each, reduced the levels of inflammatory biomarkers more than the sum of the anti-inflammatory effects of the single ingredients tested separately. The ratios of those cannabinoid molecules within the MEM formulations also greatly influenced their anti-inflammatory potential, the study reported. 

To learn more about Gb Sciences, visit www.gbsciences.com.

About Gb Sciences and GbS Global Biopharma

Gb Sciences, Inc. is a plant-inspired, biopharmaceutical research and development company creating patented disease-targeted formulations of cannabis- and other plant-inspired therapeutic mixtures for the prescription drug market through its Canadian subsidiary GbS Global Biopharma, Inc. The “plant-inspired” active ingredients in its therapeutic mixtures are synthetic homologues identical to the original plant compounds but produced under current Good Manufacturing Practices. Gb Sciences’ intellectual property portfolio contains six issued U.S. and three issued foreign patents, as well as 17 U.S. and 51 foreign patent-pending applications. In its drug development pipeline, Gb Sciences has five preclinical phase product development programs. Gb Sciences’ lead program for Parkinson’s disease is being prepared for a first-in-human clinical trial. Gb Sciences’ formulations for chronic pain, anxiety, and depression are currently in preclinical animal studies with researchers at the National Research Council Canada. The company also received positive preclinical proof-of-concept data supporting its complex mixtures for the treatment of Cytokine Release Syndrome, and its lead candidates will be optimized based on late-stage preclinical studies at Michigan State University. Gb Sciences’ productive research and development network includes distinguished universities, hospitals, and Contract Research Organizations. To learn more, visit www.gbsciences.com.

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Gb Sciences Identifies Novel Cannabis-Inspired Mixtures as Anti-Inflammatory Therapies Based on Proprietary AI-Enabled Drug Discovery Platform

Marlana DeMarco Hogan’s New Book ‘Growing Up in the Torrone Zone’ is a Delightful Children’s Story About Beloved Family Traditions Being Passed Down Through Generations

Marlana DeMarco Hogan’s New Book ‘Growing Up in the Torrone Zone’ is a Delightful Children’s Story About Beloved Family Traditions Being Passed Down Through GenerationsRecent release “Growing Up in the Torrone Zone” from Newman Springs Publishing author Marlana DeMarco Hogan is a captivating children’s book about a hardworking young boy delighting in his family’s annual torrone making. Inspired by the author’s own parents, this book pays homage to heritage and family traditions.

NEW YORK – December 22, 2022 – (Newswire.com)

Marlana DeMarco Hogan, a retired Italian teacher and the child of Italian immigrants, has completed her new book “Growing Up in the Torrone Zone”: a charming and inviting tale about an Italian family’s favorite holiday custom: making torrone.

Hogan writes, “‘Growing Up in the Torrone Zone’ is a story about a hardworking little boy and the joy he finds while helping his family to make torrone, a traditional Italian candy, for the annual town festival that takes place atop the small mountain town he calls home. Every step is filled with fun and excitement, from going down the mountain to buy the torrone ingredients to preparing the delicious candy treat. Treasured memories are made with family and friends…in the torrone zone.”

Published by Newman Springs Publishing, Marlana DeMarco Hogan’s adorable tale follows a young boy as he eagerly helps his parents make torrone for the festival. This is something he looks forward to every year and a tradition that he truly treasures – one that he plans to pass down to his children and grandchildren someday. But this isn’t just a children’s story; it is inspired by the author’s own family.

Marlana DeMarco Hogan’s father knew her mother was the one for him when she walked into his family kitchen to borrow a weigh scale as he was making torrone for their town’s annual festival. A heartwarming story told over and over again with love at family gatherings, Hogan included it. “Growing Up in the Torrone Zone” is a love letter to her immigrant parents and Italian heritage.

Readers who wish to experience this affectionate work can purchase “Growing Up in the Torrone Zone” at bookstores everywhere, or online at the Apple iBooks Store, Amazon, or Barnes & Noble.

For additional information or media inquiries, contact Newman Springs Publishing at 732-243-8512.

About Newman Springs Publishing: 

Newman Springs Publishing is a full-service publishing house for serious authors. Each title produced by Newman Springs Publishing undergoes every step of the professional publishing process, including editing, layout, cover design, circulation, distribution, and publicity. All titles are made available in both e-book and print formats. Newman Springs Publishing distributes to tens of thousands of retail outlets throughout North America and internationally. All manuscripts in any genre are welcome to be submitted for review. If the manuscript meets the necessary criteria and is accepted for publication, Newman Springs Publishing will work closely with the author to bring the book to the retail market for a relatively inexpensive initial investment.

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Media Relations
[email protected]

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Marlana DeMarco Hogan’s New Book ‘Growing Up in the Torrone Zone’ is a Delightful Children’s Story About Beloved Family Traditions Being Passed Down Through Generations

Author LucSea’s New Book ‘Ask Me, I’m Mr. What’ is an Adorable Story That Invites Readers to Learn All About the Question Word ‘What’ and How to Use It in Everyday Life

Author LucSea’s New Book ‘Ask Me, I’m Mr. What’ is an Adorable Story That Invites Readers to Learn All About the Question Word ‘What’ and How to Use It in Everyday LifeRecent release “Ask Me, I’m Mr. What” from Newman Springs Publishing author LucSea is a charming and engaging story that follows the unforgettable Mr. What as he takes readers on a journey to understand how to properly ask questions with the word “what.” No matter the situation, young readers will become pros at using Mr. What’s favorite question word to discover new things about the world.

NEW YORK – December 22, 2022 – (Newswire.com)

LucSea has completed her new book “Ask Me, I’m Mr. What”: an educational tale that invites readers to join the jovial Mr. What as he teaches all about one of the most important question words in the English language.

“‘Ask Me, I’m Mr. What’ is the second book in a series of five,” writes LucSea. “This book is an easy ‘read-aloud’ book that is intended to have children recognize words that are familiar to them. ‘What’ is one of the questions children always ask about objects and things they come across. This book also plans to initiate the awareness of colors and shapes through items they recognize through their everyday experiences. It is the second ‘must read-aloud’ book in the series of five.”

Published by Newman Springs Publishing, LucSea’s delightful tale is a wonderful tool to aid young readers in recognizing the helpful word “what” with their parents and how to use it when asking a question by reading aloud. With vibrant artwork to help bring Mr. What’s questions to life, young readers will want to revisit this interactive story over and over again, becoming masters at understanding how to ask “what” something is.

Readers who wish to experience this enlightening work can purchase “Ask Me, I’m Mr. What” at bookstores everywhere, or online at the Apple iBooks Store, Amazon, or Barnes & Noble.

For additional information or media inquiries, contact Newman Springs Publishing at 732-243-8512.

About Newman Springs Publishing: 

Newman Springs Publishing is a full-service publishing house for serious authors. Each title produced by Newman Springs Publishing undergoes every step of the professional publishing process, including editing, layout, cover design, circulation, distribution, and publicity. All titles are made available in both e-book and print formats. Newman Springs Publishing distributes to tens of thousands of retail outlets throughout North America and internationally. All manuscripts in any genre are welcome to be submitted for review. If the manuscript meets the necessary criteria and is accepted for publication, Newman Springs Publishing will work closely with the author to bring the book to the retail market for a relatively inexpensive initial investment.

Contact Information:

Media Relations
[email protected]

Press Release Service
by
Newswire.com

Original Source:

Author LucSea’s New Book ‘Ask Me, I’m Mr. What’ is an Adorable Story That Invites Readers to Learn All About the Question Word ‘What’ and How to Use It in Everyday Life